According to statistics, approximately 30% of adults suffer from chronic pain, and there are at least 100 million pain patients in China. Two out of every three outpatients are patients with various pain conditions or symptoms, and most pain patients have been diagnosed or treated by more than one specialty. According to the professor, pain has been ranked as the fifth most important vital sign after respiration, pulse, blood pressure and body temperature. Chronic intractable pain includes trigeminal neuralgia, postherpetic neuralgia, reflex sympathetic dystrophy, cancer pain, etc.; there are also some migraine, low back pain, joint pain, etc. If they are not treated timely and effectively, they can also turn from local long-term common pain to complex local pain syndrome or central pain, which becomes very intense and becomes intractable pain. Pain medicine (Pain clinic) is an emerging edge discipline integrated with neurology, anesthesiology, radiation intervention, and orthopedics, and pain medicine and adjacent disciplines treat “pain” with each other, but also have a clear division of labor. For example, anesthesiology focuses on pain relief and treatment of acute pain during surgery, western orthopedics focuses on surgery for bone injuries, Chinese orthopedics focuses on manual therapy, neurology and oncology focus on drugs, and rehabilitation physiotherapy focuses on physical methods. The treatment of pain medicine has shifted from simple drug treatment to multidisciplinary treatment, in which the effect of minimally invasive neurological treatment by imaging intervention is more prominent. The exact expression should be “imaging and electrophysiologically guided interventional minimally invasive neurosurgery”, that is, with reference to the electrophysiological response of the target area, selective, destructive nerve block or precise focal treatment under X-ray or CT guidance, blocking the transmission of pain signals or relieving the compression of nerves. This technique has relieved or eliminated many intractable pains that could not be relieved by original drugs; post-stroke pains and central pains that used to require invasive treatment in the skull can now be relieved without craniotomy. Not only painful diseases such as intractable nerve, cancer pain, phantom limb pain, but also some painless diseases of other disciplines, such as facial or eye muscle spasm, paralysis, vertigo, tinnitus, allergic rhinitis, retinal vascular occlusion, intractable eruption, angina pectoris, cerebral vascular spasm, thrombosis, infarction, peripheral vascular disorders, menstrual disorders, etc., can also be treated by nerve stimulation or blockade. China’s pain specialist has not been formally included in the medical establishment, doctors do not understand the phenomenon of pain medicine is not uncommon, many people are still stuck in the “pain is only a symptom” of the old concept, every encounter with an unknown cause of pain, rarely think to ask the pain department consultation. Of course, because most of the treatment methods in China are still analgesic drugs plus traditional massage, traction, hot compresses, acupuncture, etc., there are not many treatments that can directly target the “root” of chronic intractable pain, and minimally invasive interventions for neuralgia have not been widely used, resulting in the unique effect of pain medicine has not been fully revealed. In tens of thousands of hospitals across the country, pain departments equipped with modern pain medicine theory and technology, pain wards are not yet common. It is no wonder that many people misunderstand that the treatment of pain is only “treating the symptoms but not the root cause” and “not solving the problem”. In fact, chronic intractable pain is a disease in itself, can relieve their pain, of course, is the cure for the “root”.