The presence of hives on the face is not directly related to the severity of the disease, but rather to whether it is accompanied by the involvement of other important organs. In the absence of other accompanying symptoms, urticaria on the face is a relatively common skin disease and is not considered serious. Urticaria is an allergic disease whose severity is related to the clinical presentation. The vast majority of patients only manifested in the skin surface with intense itching of the wind, the rash can develop in various parts of the body, including the face, head, trunk, limbs, etc., this situation by the general simple anti-allergy treatment, the symptoms can be improved, and does not belong to the serious disease. When urticaria involves the gastrointestinal mucosa, respiratory mucosa and infection, it represents a more serious condition. 1. Edema of the gastrointestinal mucosa is characterized by nausea, vomiting and abdominal pain. 2. Edema of the respiratory mucosa is characterized by chest tightness, palpitations, dyspnea, and asphyxia. 3. Infections can lead to systemic symptoms such as fever and chills. Treatment of urticaria, according to the clinical manifestations of different, choose a different treatment program, the specific circumstances need to strictly follow the doctor’s instructions.