With an aging population and modern transportation, spinal disorders have become common and frequent diseases that affect people’s lives, and many of them require surgical treatment. However, the three-dimensional anatomy of the spine is complex, adjacent to important neurovascular tissues, and many important anatomical structures are invisible during surgical operations, relying only on the surgeon’s experience and imprecise methods such as fluoroscopy, so many surgeries are risky and have many complications, leading many patients to be very afraid of surgery. More reliable and safer surgical techniques have become a common goal for spine surgeons and patients. In recent years, with the increasing maturity of computer technology and precision mechanical automation, navigation technology has gradually become a high technology to improve the accuracy and safety of spine surgery. The basic principle of computerized navigation technology for spine surgery is similar to the familiar vehicle-mounted satellite positioning system (GPS) and long-range missiles, using three-dimensional CT images of spinal structures. The surgeon no longer needs to make a large incision in the patient’s body, but only needs a smaller surgical incision or even minimally invasive percutaneous surgery to complete a variety of difficult spine surgeries very safely. It can be said that computer navigation technology has given the surgeon a pair of eyes that can see through. Our research in computerized navigation technology for spine surgery has been in the leading position internationally, and many operating specifications and surgical techniques have been developed by our research. Using this technology, difficult surgeries such as “nailing” (internal fixation with pedicle screws and internal fixation of the upper cervical spine) and correction of severe spinal deformities have become very easy. Moreover, procedures that previously required large incisions to complete can be accomplished through minimally invasive percutaneous methods, reducing surgical injuries. Computer navigation technology has heralded the development of intelligent surgery and laid the foundation for the exploration of robotic surgery technology, which may become a requirement for spine surgery in every hospital in the future. Spine surgery will become minimally invasive and safe, and no one will have to fear surgery anymore.