Multidrug-resistant tuberculosis (MDR-TB) is tuberculosis in which the tubercle bacilli are resistant to at least two or more drugs, namely isoniazid and rifampicin. There are two definitions of MDR-TB, some consider resistance to any two or more antituberculosis drugs as MDR-TB; others consider MDR-TB to mean resistance to both H and R, regardless of resistance to other drugs; 2. 2. Multidrug-resistant TB (MDR-TB) is mostly acquired resistance and is therefore common in cases that have failed treatment with INH-containing, RFP-retreatment regimens and in patients with chronic detoxification, although a few are primary multidrug-resistant. Primary MDR-TB refers to MDR-TB strains that occur in patients without a history of tuberculosis and who have not received anti-tuberculosis treatment for the first time. In October 2006, the World Health Organization (WHO) defined XDR-TB as a disease that is not only resistant to isoniazid and rifampicin, but also resistant to any fluoroquinolones and at least one of the three second-line injectable drugs (capreomycin sulfate, kanamycin, and amikacin). Star) to at least one of the three second-line injectable drugs.