Drug treatment and surgical options for trigeminal neuralgia

  Trigeminal neuralgia is a common condition and many patients suffer from it for a long time. I will use my free time to gradually improve this introduction.  The cause of trigeminal neuralgia is mostly caused by the compression of cerebral blood vessels at the root of the trigeminal nerve. Therefore, the most effective treatment is to isolate the compressed blood vessels from the trigeminal nerve through craniotomy, i.e. microvascular decompression MVD. The main drug treatments are carbamazepine, phenytoin sodium and oxcarbazepine. The cheapest and most effective is carbamazepine, but the large amount has side effects such as causing dizziness. Since the nerves are compressed by blood vessels for a long time, long-term medication will be ineffective and patients will eventually have to undergo other surgical treatments to stop the pain. Therefore, drug treatment is suitable for patients with new onset of disease and elderly patients.  Surgical treatment includes: 1. MVD is the most effective radical treatment method, with an efficiency of about 95% and a low long-term recurrence rate of about 5%. The disadvantage is that general anesthesia is required for craniotomy, which has certain surgical risks, but the mortality rate is close to 0 at present. No obvious complications are generally left after surgery, as long as very few patients can have tinnitus hearing loss. It is suitable for all patients who can tolerate the surgery with a life expectancy greater than 5 years.  2.Trigeminal nerve sensory root partial excision. It is used for the proposed trigeminal nerve microvascular decompression procedure when no obvious vessels are found to be compressing the trigeminal nerve during surgery. Because a small number of patients are found to have no obvious vascular compression of the trigeminal nerve root during surgery, part of the nerve must be cut to achieve pain relief. Postoperative facial numbness is left behind. The effect is permanent and the recurrence rate is low.  2. Trigeminal nerve hemianopsia radiofrequency thermocoagulation. Under local anesthesia, an electrode needle is inserted into the outer corner of the mouth to the cranial exit of the trigeminal nerve, that is, the meniscal ganglion, and the nerve is destroyed by electricity to achieve pain relief. The effect usually lasts for about 2 years, but there are some that last up to 10 years. It is not suitable for people with pain in the frontal region, the first branch of the trigeminal nerve, because this nerve innervates the eye and destruction can lead to keratitis and blindness. It is suitable for elderly people with 2.3 branches of pain who cannot tolerate craniotomy because of the ineffectiveness of drugs. 3. Local nerve closure, the same principle as above, with shorter maintenance time. Suitable for elderly patients with poor physical condition 4.Gamma knife radiotherapy, through gamma radiation destruction of the intracranial trigeminal nerve root, low efficiency, about 50%. The recurrence rate is high, maintaining an average of 2 years. Suitable for patients who can not accept surgery and drug ineffective.