Normal breast compression does not cause pain. If there is pain on breast compression, prompt examination and treatment is required. Under normal circumstances, women do not experience pain when pressing their breasts. If there is pain when pressing the breasts, there may be abnormalities and the cause of the pain needs to be identified. There are many clinical reasons for breast pain, but in adolescence it is mainly due to compensatory hyperplasia of the mammary glands, which is a normal physiological phenomenon, manifesting as an increase in breast volume and pain when pressed, and such patients do not need treatment. In addition, patients with breast enlargement may also experience pain when pressing their breasts, mainly due to an imbalance in the ratio of estrogen to progesterone. In addition, special attention should be paid to malignant tumors of the breast, which can also cause painful breast compression and a palpable lump. If the pain is caused by pathological factors, the patient should undergo targeted treatment under the guidance of a doctor.