The symptoms of atrial deficiency may not be obvious in many patients, and some patients may have symptoms of chest tightness and shortness of breath in the late stage, and if combined with atrial fibrillation, they may have symptoms of panic. Because this disease will progress, if it is severe, the right ventricle will enlarge and the pulmonary artery pressure will increase due to the severe left-to-right shunt, and if the history is long enough, the pulmonary artery pressure will keep increasing and increase to a very serious degree. In severe pulmonary hypertension, the left-to-right shunt will decrease, and a bidirectional shunt will appear, or even a right-to-left shunt will predominate, and the patient will have obvious chest tightness and shortness of breath, as well as cyanosis of the lips and nails. Once it reaches this level, there may be no chance for further treatment, no matter doing interventional blockage or surgery. Therefore, if a suspicious condition is found on physical examination, the patient should be advised to have a cardiac ultrasound, and if the disease is clearly identified, surgical treatment will be performed depending on the size of the defect.