2015 ACS Summary of Guidelines Regarding Cancer Screening The summary was published in CA and is a heavyweight article in the annual ACS. The table below shows the recommendations for early screening for breast, cervical, colorectal, endometrial, and prostate cancers among routine risk, asymptomatic adults and early screening for lung cancer among high risk, asymptomatic adults. Regarding cervical cancer screening, there are two changes from the 2012 ASCCP guidelines (2013). Based on the Kaiser Permanente Northern California (KPNC) database, the 2013 management guideline recommends that women who are HPV-positive and ASCUS be rescreened within 3 years, rather than within 4 years, and emphasizes that there is insufficient evidence to suggest that HPV-negative, ASCUS results at age 65 can no longer be screened. The second change is the FDA’s approval of HPV testing as the preferred cervical cancer screening option, meaning that HPV becomes a separate screening option without the need for concurrent cytology. Of course, the ACS has taken these two changes fully into account, and the overall principles have included these considerations.