The duration of the burning sensation after the application of cold compress is mainly based on the individual patient’s condition and cannot be generalized. The cold patch is mainly used for sprains and burns in the early stage of the patient, the cold patch can promote vasoconstriction to avoid the hematoma to continue to increase. There are two cases of burning sensation after applying cold compress, one is normal reaction, the patient’s symptom only has burning sensation and will not be aggravated progressively, the burning sensation will subside within 1 day; the other case is allergic reaction, mainly manifested as local burning, tingling, itching, rash and other symptoms, which may be due to the patient’s allergy to the mint and blood stasis activating drugs in the cold compress, the duration of burning sensation is related to the degree of allergic reaction. The duration of the burning sensation is related to the degree of allergic reaction, and cannot be generalized. Therefore, after applying the cold compress, you should pay attention to the skin reaction of the area, if there is allergy, you should remove the cold compress and rinse it with water, if the allergic reaction is serious, it is recommended to go to the hospital dermatology department.