Acute biliary pancreatitis clinical manifestations have the following ten points: 1, abdominal pain the most important symptom is mostly sudden epigastric or left epigastric persistent severe pain or knife-like pain, epigastric waist is girdle feeling, often occurs after a full meal or drinking, accompanied by paroxysmal intensification, can be enhanced by eating, can spread to the umbilicus or the whole abdomen. It often radiates to the left shoulder or both sides of the low back. The pain site is usually in the middle and upper abdomen, such as inflammation of the head of the pancreas is predominant, often in the right side of the middle and upper abdomen; such as pancreatic body and tail inflammation is predominant, often in the middle and upper abdomen and left upper abdomen. Pain can be reduced when bending or sitting forward. Sometimes morphine alone is not effective, if combined with bile duct stones or biliary ascaris, there is right upper abdominal pain, biliary colic. 2, nausea and vomiting 2/3 of patients have this symptom, frequent attacks, early reflex, the content of food, bile. Late stage is caused by paralytic intestinal obstruction, the vomit is fecal-like. If you vomit roundworms, it is mostly pancreatitis complicated by biliary ascariasis. In alcoholic pancreatitis, vomiting often occurs during abdominal pain, and in biliary pancreatitis, vomiting often follows the onset of abdominal pain. 3, abdominal distension in heavy cases caused by the irritation of intra-abdominal exudate and retroperitoneal hemorrhage, paralytic intestinal obstruction causing pneumatization and fluid accumulation in the intestine causes abdominal distension. 4, jaundice about 20% of patients with varying degrees of jaundice 1 to 2 days after the disease. The cause may be the coexistence of bile duct stones, causing bile duct obstruction, or enlarged pancreatic head compression of the lower end of the common bile duct or impaired liver function jaundice, the heavier the jaundice, the more serious the disease, the prognosis is poor. 5, the fever is mostly moderate: between 38 ° ~ 39 ° C, generally 3 to 5 days after the gradual decline. However, in heavy cases, the fever can last for many days without decreasing, suggesting pancreatic infection or abscess formation and toxic symptoms, and in severe cases, the body temperature may not rise. When combined with cholangitis, there can be chills and high fever. 6, hand and foot convulsions as a result of reduced blood calcium. It is the action of lipase that enters the abdominal cavity, so that the fatty tissue on the large omentum and peritoneum is digested and decomposed into glycerol and fatty acids, the latter combined with calcium as insoluble fatty acid calcium, and thus serum calcium decreases, such as serum calcium 100mg%, renal failure, etc. 7, acute respiratory failure whose clinical characteristics are the sudden onset of progressive respiratory distress, hyperventilation, cyanosis, anxiety, sweating, etc., conventional oxygen therapy can not make it ease. 8, acute renal failure 23% of those with severe acute pancreatitis can develop acute renal failure, with a mortality rate of up to 80%. The cause of its occurrence is related to the role of hypovolemia, shock and pancreatic kinin. Pancreatic enzymes cause abnormal blood clotting and a hypercoagulable state, producing microcirculatory disorders and leading to renal ischemia and hypoxia. 9, circulatory failure severe pancreatitis can cause heart failure and arrhythmia, the latter can be cool like myocardial infarction. 10, pancreatic encephalopathy incidence of about 5.9%-11.9%, manifested as neuropsychiatric abnormalities, lack of orientation, mental confusion, accompanied by fantasy, hallucinations, manic state, etc.. It is often transient and can return to normal completely, but can also leave behind mental abnormalities.