A less common type of refractory asthma: Recently, some patients with allergic bronchopulmonary aspergillosis (ABPA) have been focused on. These patients mainly present with recurrent intractable asthma, cough, cough with white, yellow and brown sputum, allergen-positive mainly Aspergillus fumigatus, some patients with concomitant dust mite and other mold allergy, showing elevated total IgE and elevated blood eosinophils on testing, and some patients with pulmonary CT shows bronchiectasis, and the general treatment is not effective. Therefore, for patients with persistent asthma, total IgE testing should be performed, and if necessary, they should come to the hospital’s Department of Allergic Reactions for testing of Aspergillus fumigatus-specific IgE and IgG to clarify the diagnosis and carry out targeted treatment.