Azithromycin is a macrolide antibiotic with good efficacy in bronchopneumonia caused by mycoplasma and chlamydia infections. If the patient is checked positive for mycoplasma and chlamydia antibodies, azithromycin can be used for treatment. However, with clinical application, a certain degree of drug resistance has also emerged. If the patient’s treatment is not effective, adults over 18 years old can also consider using quinolones for treatment, such as levofloxacin and moxifloxacin tablets, which can also achieve significant results. In case of bronchopneumonia caused by bacterial infection, azithromycin is generally effective. Penicillins, cephalosporins or quinolones can be chosen to treat bronchopneumonia caused by bacterial infection, which can have significant efficacy.