”Gout is a hereditary disease with a family history, the incidence of which has increased in recent years. It is a metabolic disease caused by disorders of purine metabolism, mainly inflammatory changes in the joints, connective tissue and kidneys. When uric acid, a purine metabolite, is produced in excess of the kidney’s ability to excrete it, it accumulates in the blood and tissues, forming “gout”. During acute attacks, it often manifests as joint pain, redness and swelling, and is easily misdiagnosed as “rheumatic” arthritis. The difference between the two Gout is almost always seen in men over 40 years of age, and often manifests as a sudden onset of severe pain at night, mostly with acute arthritis, which starts with redness, swelling and pain, peaks in 72 hours, and can disappear on its own in a week or two, and then reappears for several years. When eating a diet containing a lot of purines, such as animal offal, sardines, yeast, tobacco, alcohol, etc., high uric acid accumulation in the blood and tissues is prone to the formation of gout stones, mostly around the toe bones and joints, and also kidney stones, etc. Acute rheumatoid arthritis is an allergic disease related to streptococcal infection. It is often seen in adolescents, mostly after the joints have been affected by rheumatism, and often manifests in large joints, such as knees, ankles, elbows, wrists and other joints with wandering arthritis, and heart muscle and valve damage at the same time, which means that the disease can manifest “licking the joints and biting the heart” at the same time. The treatment for both is very different. Gout is treated with anti-purine metabolism and uric acid excretion drugs, such as colchicine, to control symptoms. Rheumatoid arthritis is treated with salicylic acid drugs. As time passes, gout is easily confused with rheumatoid arthritis due to repeated attacks on the joints, not only tissue damage, but also erosion of the joint ends of the bone, plus the deposition of gouty stones, which cause chronic inflammation and joint deformities. Rheumatoid arthritis is a chronic systemic autoimmune disease with predominantly joint lesions. It is hereditary, chronic and persistent, with an unclear etiology, and is associated with a combination of factors. Without timely treatment almost all internal organs can be involved: destructive lesions can occur in all joints, causing slow deformation of joints, ankylosis, chicken claw shape of hands, loss of function and even paralysis, atrophy of bones and skeletal muscles, often accompanied by extra-articular symptoms, and positive rheumatoid factor can be seen in laboratory tests. The three are not difficult to distinguish Gout is easily diagnosed, and can be determined by measuring elevated blood uric acid and feeling for gout stones. Rheumatoid arthritis alone is rare and is mostly a large arthritis. In the acute stage, there is mostly rheumatic myocarditis, and in the chronic stage, there is “rheumatic heart disease”. The test is positive for Anti-Strand O (ASO). Rheumatoid arthritis is a chronic and persistent disease, with joint deformity, significant loss of function, stiffness or paralysis, and positive rheumatoid factor. What are the differences between rheumatoid and rheumatoid rheumatoid arthritis and rheumatoid arthritis Although there is only one word difference, the disease symptoms are very different. Rheumatoid arthritis is a manifestation of rheumatic fever. Rheumatic fever is a systemic metabolic disease caused by group A, type B, hemolytic streptococcal infection, which often starts with a history of infection such as dengue. The onset of rheumatic fever is rapid, and it is most often seen in adolescents. Rheumatoid arthritis can invade the heart and cause rheumatic heart disease with fever, subcutaneous nodules and rash. Rheumatoid arthritis has two characteristics: First, the joints are red, swollen, hot, painful and can not move, the onset of the site is often the knee, hip, ankle and other large joints of the lower limbs, followed by the shoulder, elbow, wrist joints, the small joints of the hands and feet are rare; second, the pain is wandering, a period of time is this joint attack, a period of time is that joint discomfort, but the pain does not last long, a few days can subside. The blood sedimentation is accelerated, the anti-“0” titer is increased, and the rheumatoid factor is negative. After treatment, recurrence is rare, and the joint does not remain deformed, and some patients can be left with cardiac lesions. Rheumatoid arthritis is an autoimmune disease that is not hereditary, but may be related to genetic factors and occurs in women between the ages of 20 and 40. The early symptoms are mostly joint pain, swelling, stiffness, and limited mobility, which can be mild or severe, recurrent, and persistent, often leaving behind ankylosing deformities of the bones and joints. Although a few patients may have cardiovascular disease, the vast majority of patients have no cardiac symptoms and are positive for rheumatoid factor. This shows that although rheumatism and rheumatoid are both arthritis and both have joint pain symptoms, they are not the same disease and should not be confused.