1.Does allergic purpura cause kidney damage?
1.Why does allergic purpura damage kidney and what are the chances that patients will develop nephritis?
Allergic purpura is a small vasculitis with four main organs involved, namely skin, joints, gastrointestinal tract and kidneys. About half of the cases of allergic purpura will have more or less kidney involvement. Allergic purpura involving the kidneys is a more serious condition and requires diagnosis and treatment by a nephrologist. Special attention is needed: once diagnosed with allergic purpura, be sure to check if there is kidney involvement.
2, how long after the appearance of allergic purpura will appear purpura nephritis?
It usually appears and is found at the same time, or it can be later than days or even years after the skin purpura. Therefore, once diagnosed with allergic purpura, not only should we check whether there is kidney involvement during acute attack, but it is better to review urine examination every 1-2 years after the skin purpura disappears later. In order to determine whether purpura nephritis appears.
3.Does the medication for allergic purpura damage the kidneys?
Usually not.
4.What are the symptoms when kidney damage occurs? How much will the blood pressure rise and will there be hematuria in the naked eye?
The main symptoms are proteinuria, hematuria (occult blood), hypertension, and in severe cases, hematuria (blood in urine), elevated blood creatinine, and even oliguria and acute renal failure.
5, purpura nephritis will cause permanent damage to the kidneys, will lead to uremia, will be life-threatening?
Most children with purpura nephritis tend to heal, however most adults with purpura nephritis tend to cause permanent kidney damage, about 20% of patients may develop uremia in the future. Due to advances in dialysis technology, it is generally not life-threatening, but can be life-threatening if serious side effects occur during treatment.
6, can purpura nephritis be completely cured?
Most children purpura nephritis can often be cured, but most adults purpura nephritis will develop into chronic glomerulonephritis, the current drugs can control the progression of the disease in most patients, but can not be cured.
Second, purpura nephritis need to develop a treatment plan according to the stage of the disease
The actual fact is that you will be able to get a lot more than just a few of these. Can patients who are not suitable for kidney puncture develop a treatment plan through laboratory tests only?
Renal puncture is required for moderate or severe purpura nephritis. The usual criteria are: urine protein greater than 1g, or the presence of hypertension, elevated blood creatinine, or sarcoid hematuria. Patients who are not suitable for renal puncture can also choose their treatment plan based on clinical manifestations only.
2, purpura kidney patients simply present with microscopic hematuria (isolated hematuria), why only need to be treated for allergic purpura? Will the nephritis develop further without medication?
If you have submicroscopic hematuria (isolated hematuria), the nephritis is usually mild and no special medication is needed. Of course, nephritis may develop further, so regular review is needed for timely detection and then treatment.
3, which patients should be treated with antihypertensive drugs, what are the effects of the drugs, and will hypotension occur in patients with normal blood pressure after taking the drugs?
Regardless of whether there is hypertension, patients with purpura nephritis will generally be given “Satan” or “Pulley” type of drugs, the purpose of which is two. First, to reduce urine protein and protect kidney function; second, to lower blood pressure in patients with hypertension. Even patients without hypertension are often asked to take these drugs, unless their blood pressure is too low after taking them (consistently below 100/60mmHg).
4. Which patients should be treated with hormones and when do they need hormones combined with immunosuppressive therapy? How long does it take to control the progression of the disease?
Severe purpura nephritis requires hormone therapy in the acute phase. It usually takes at least six months to control the progression of the disease.
5. Are patients prone to malnutrition and osteoporosis?
After taking hormones, osteoporosis may occur, so calcium supplementation is needed. Generally, malnutrition will not occur.
6.What is shock therapy and which patients need to do shock therapy?
Shock therapy refers to high-dose intravenous hormone shock therapy. It is for the most serious part of patients with purpura nephritis. For example, the presence of carnal hematuria, oliguria, acute renal insufficiency, and a large number of fresh crescent bodies seen by kidney puncture.
7.What are the side effects of shock therapy and how to relieve them?
The main side effect is infection.
8.Which patients need to do plasma exchange? Is it possible to interrupt the course of treatment once the disease indicators are found to be stable?
Generally, plasma exchange is not done.
9.How often should patients be seen again and what tests should be done?
The follow-up should be once every 1-6 months. In severe cases, or if the treatment plan is changed, once every 1-2 months, and in stable cases, once every 4-6 months. If the disease is stable for a long period of time, the follow-up examination should be conducted once every 6-12 months. We will give you the checkups for the follow-up, so you can bring them directly to the hospital next time.
10.How long does it take to see the effect of the treatment?
Usually about 6 months.