The dosage of methylprednisolone tablets for patients with purpura nephritis is usually 0.4-0.8 mg per kilogram of body weight per day, and the maximum dosage is usually not more than 48 mg.
Purpura nephritis is mainly an autoimmune disease, after the application of sufficient amount of ACEI or ARB drugs still urine protein quantitative greater than 1 grams of patients can try glucocorticoid therapy, glucocorticoid clinically generally refers to prednisone acetate, methylprednisolone.
Prednisone acetate dosage is controlled at 0.5-1.0 mg per kilogram of body weight per day, with the maximum dose not exceeding 60 mg. Converted to methylprednisolone is 0.4 to 0.8 milligrams per kilogram of body weight per day, with the maximum dose not exceeding 48 milligrams, or 12 tablets of methylprednisolone per day.
Methylprednisolone has more serious side effects, especially when the hormone dosage is large, it is prone to femoral head necrosis, peptic ulcers, serious infections, osteoporosis and other complications, so it is necessary to use the drug under the guidance of a doctor and reduce the dosage in a timely manner according to the condition, and should not be applied in large doses for a long time.
Patients with purpura nephritis are advised to consult regular hospitals in time and standardize the use of medication and reduce the dosage under the guidance of physicians.