The best time to take medicine three times a day mainly depends on the type of medicine taken, some drugs may be better taken before meals, some drugs may be better taken during or after meals. For example, the commonly used clinical gastric mucosal protection drug Methylphenidate is recommended to be taken orally half an hour before meals in order to play a role in protecting the gastric mucosa. There are also some drugs recommended to be taken after meals, such as aspirin, a drug that is more stimulating to the gastrointestinal tract, and some water-soluble vitamins, are recommended to be taken after meals. So different drugs must be taken at the time of application under the guidance of a doctor’s standard, or according to the instructions to decide when to take. The chemical nature of different drugs is different, and the relationship with diet is also determined, so be sure to follow the doctor’s instructions. And during the period of using the drug, you should pay attention to avoid eating greasy, cold, spicy and other stimulating food, and try to take it with warm boiled water.