Type 2 diabetes may go into remission. Type 2 diabetes in remission is defined as having blood glucose that remains in an attained or normal state in the absence of glucose-lowering medication. There is no evidence that type 2 diabetes is cured, and after remission of type 2 diabetes, even though the measures that led to remission are maintained, blood glucose levels can rise again in some patients to levels that require control with glucose-lowering medications. Remission of type 2 diabetes is associated with correction of obesity or significant improvement in body mass, improvement of fatty liver and fatty pancreas, improvement of insulin resistance and hyperinsulinemia, correction of hyperglycemic toxicity, and pancreatic beta-cell dedifferentiation and transdifferentiation. Patients with type 2 diabetes need to test their blood glucose values regularly and seek medical attention if they have abnormal blood glucose values.