How does ovarian polycystic form and how does it need to be treated?

Ovarian polycystic in clinical practice generally means suffering from polycystic ovary syndrome, one of the most common gynecological endocrine disorders, characterized by persistent anovulatory and ovarian polycystic changes with clinical or biochemical manifestations of hyperandrogenism, often accompanied by insulin resistance and obesity. Current research suggests that it may be due to the interaction of certain genetic and environmental factors, and may be related to the following causes: 1. abnormal regulation of the hypothalamic-pituitary-ovarian axis: increased sensitivity of the pituitary gland to gonadotropin-releasing hormone, increased secretion of luteinizing hormone, and excessive production of androgens, resulting in ovarian polycystic changes; 2. insulin resistance and hyperinsulinemia: the body’s sensitivity to insulin The sensitivity of insulin becomes low, and about half of the patients have different degrees of insulin resistance and compensatory hyperinsulinemia, which act on the pituitary gland to increase the release of luteinizing hormone and increase the secretion of androgens; 3, abnormal adrenal function: caused by abnormal hyperadrenal function. Treatment modalities: 1. Weight loss: If the patient is obese, he should control diet and increase exercise to reduce weight, which is conducive to increasing insulin sensitivity; 2. Regulate menstrual cycle: Use combined estrogen and progestin therapy to inhibit the secretion of luteinizing hormone and reduce the secretion of androgens in the body; 3. Reduce blood androgen levels: Glucocorticoid steroids, cyproterone, spironolactone, etc. can be used for pituitary 4.Improve insulin resistance: For obese patients or patients with insulin resistance, insulin levels can be reduced to help correct the high androgen status, and ovarian function can be improved. 5.Surgical treatment: Laparoscopic ovarian perforation and Hyster minimally invasive surgery can be performed, which can also increase the chance of pregnancy and reduce the risk of miscarriage.