Early stage breast cancer often does not have typical signs and symptoms and is not easily noticed, but is often detected through physical examination or breast cancer screening. The following are the typical signs of breast cancer. Breast lumps 80% of breast cancer patients are first diagnosed with breast lumps. Breast lumps are often found unintentionally, most of them are single, hard, with irregular edges and less smooth surface. Most breast cancers are painless lumps, only a few are accompanied by varying degrees of vague pain or stabbing pain. Nipple overflow is called nipple overflow when there is blood, plasma, milk or pus flowing from the nipple during non-pregnancy period, or when there is still milk flowing after stopping breastfeeding for more than half a year. There are many causes of nipple overflow, and common diseases include intraductal papilloma, mastopexy, ductal dilatation and breast cancer. Unilateral hemorrhagic overflow from a single hole should be further examined, and more attention should be paid if it is accompanied by breast lumps. The most common one is that the tumor invades Cooper’s ligament which connects the breast skin and deep pectoral muscle fascia, causing it to shorten and lose its elasticity, pulling the skin of the corresponding area, resulting in “dimple sign”, i.e. a small dimple in the breast skin, like a small dimple. If the cancer cells block the lymphatic ducts, “orange peel-like changes” will appear, i.e. the skin of the breast will have many small dots and depressions, just like an orange peel. In advanced stage of breast cancer, the cancer cells infiltrate into the skin along the lymphatic ducts, glandular ducts or fibrous tissues and grow into the skin, forming scattered hard nodules around the main cancer site, which is called “skin satellite nodules”. 4.Abnormality of nipple and areola Tumor located in or close to the deep part of nipple may cause nipple retraction. If the tumor is far away from the nipple, it may also cause nipple retraction or elevation when the large duct in the breast is invaded and shortened. Eczema-like carcinoma of the nipple, i.e. Paget’s disease of the breast, manifests as itching, erosion, rupture, crusting, flaking and burning pain of the nipple skin, resulting in nipple retraction. 5. Axillary lymph node swelling More than 1/3 of breast cancer patients have axillary lymph node metastasis. At the initial stage, the lymph nodes in the ipsilateral axilla may be swollen, and the swollen lymph nodes are hard, scattered and pushable. As the disease progresses, the lymph nodes will gradually fuse and adhere to the skin and surrounding tissues. In the advanced stage, metastatic lymph nodes can be felt in the supraclavicular and contralateral axillae.