Patient: Description of the condition (onset time, main symptoms, hospital visited, etc.): I had my first cervical LEEP knife conization surgery at Beijing Daxing Hospital on April 30, 2003, and the results of my gynecological physical examination scrapings in 2009 and 2010 were cervical precancerous lesions CIN1-CINII, and I had a colposcopic biopsy in December 2009, and the results were also cervical precancerous lesions CIN1-CINII. The results were also cervical precancerous lesions CIN1-CINII, positive for HPV, one of the 13 high-risk viruses, containing 579. On August 31, 2010, she underwent a second LEEP knife conization at Beijing Daxing Hospital, and the surgical pathology showed: cervical point 3.6.9.12 and other biopsies: chronic cervical and endocervical inflammation. Both treatments were LPPP surgery, only 3 boxes of artificial recombinant interferon a-2b were used from March to May 2010, no other treatment was used, the results were not good. the HPV value was increasing! And, 10 days after the end of the period there is also a brown discharge with red blood! I want to know how to cure HPV positive high risk virus. 2. 10 days after my period, I still have brown discharge with red blood! What is the problem that this state takes 5-6 days and that the lumbosacral bone is always sore and gets better when I get up after a nap? How should I treat it? 3. How can I treat chronic cervical and endocervical inflammation? Thank you so much! Please be able to help me! Miao Jinwei, Department of Gynecology, Beijing Maternity Hospital: Your condition is complicated, you have been treated with interferon and had two LEEP procedures, but the results are still unsatisfactory, so you may have to consider whether you should have a cold knife conization with a greater scope than LEEP, and given that you have already experienced 2 procedures before, you should go to the hospital for a systematic preoperative evaluation before this procedure. Patient: Well, yes! Thank you!