When ascites occurs in bile duct tumor, first of all, the grading and staging of the tumor should be clarified first, and then according to the grading of the tumor, targeted treatment should be carried out. If the bile duct tumor is in advanced stage, it can only be treated by nutritional support to protect liver, and when the ascites is serious, it can be relieved by puncture drainage and albumin supplementation. If the bile duct tumor is not in advanced stage, ascites can be relieved by actively transfusing albumin to enhance the level of albumin in the body, and diuretics such as furosemide and spironolactone can also be used to reduce ascites. When the nutritional status is good, the bile duct tumor can be treated by radical surgery (such as pancreaticoduodenectomy), so that the bile duct tumor can be eradicated. For ascites caused by bile duct tumors, it is necessary to clarify the cause of ascites formation, whether there is a combination of other problems, and carry out targeted treatment under the guidance of doctors.