The main drugs used to treat Mycoplasma pneumoniae infection are macrolides, quinolones, tetracyclines, etc. Macrolides include azithromycin, roxithromycin, clarithromycin, etc. The more commonly used one is azithromycin, which is a long-acting oral drug with two treatment options, and patients are advised to make sure to read the instructions before using the drug. The quinolones mainly include levofloxacin, moxifloxacin hydrochloride, ciprofloxacin, etc. If the age >18 years old for mycoplasma infection, it is still recommended to apply the quinolones. Due to the abuse of antimicrobial drugs in China now, the resistance rate of mycoplasma to macrolides is very high, so it is better to use quinolones for those aged >18 years. But if <18 years old, only macrolides can be used, because quinolones are prohibited under 18 years old. Tetracyclines have relatively more side effects, and especially for children may also have tetracycline teeth, and are generally used only when there is no drug of choice.