Advanced breast cancer is not untreatable and there are many options available. When choosing a treatment option, you need to consider the following: age, menopause, hormone receptor status, HER-2 status, whether you have already received some kind of anti-cancer treatment before, the site and extent of metastasis, the speed of tumor progression, and the effectiveness of previous chemotherapy or endocrine therapy. Patients need to discuss with their supervising physician which treatment is suitable for them. The main methods of treatment for breast cancer include: 1. Surgery: Surgery is generally not a major means for advanced breast cancer. However, for patients with local recurrence, regional lymph node metastasis, or a single metastasis, surgical excision may sometimes be an option. Even if surgery is chosen, it is usually combined with systemic drug therapy. 2.Radiation therapy (radiotherapy): For local recurrence, regional lymph node metastasis, bone metastasis and metastasis in certain other areas, radiotherapy can play a better role in palliative treatment or pain relief. 3.Chemotherapy (chemotherapy): Anti-cancer drugs can destroy tumor cells. This treatment is usually administered intravenously in the hospital, and some drugs can be taken orally. These patients need to take a break for a few days or weeks between treatment cycles. The details will depend on the patient’s chemotherapy regimen. This again allows the patient to recover from the side effects of chemotherapy. 4. Endocrine therapy: These drugs work by inhibiting the body from producing or using a certain hormone. In most cases, that hormone is estrogen. These drugs can inhibit or stop the growth of the tumor. In some patients, these drugs can cause the tumor to shrink. 5. Biological therapy: Biologically targeted therapeutic drugs are a hot research topic in recent years. Currently developed drugs mainly target human epidermal growth factor receptor-2 (HER-2, a protein produced by oncogene, which is related to tumor growth) and tumor blood vessels. The rational use of the above therapies can effectively prolong the survival and improve the quality of life of patients with advanced breast cancer, and some patients can even survive for a long time.