How to properly understand herpes simplex virus and genital herpes

  Genital herpes is a recurrent disease caused by herpes simplex virus (HSV) infection of the skin and mucous membrane of the genital and anal areas of the urinary tract, and is a common sexually transmitted disease. there are two types of HSV: HSV-1 and HSV-2, and most genital herpes is caused by HSV-2.  2. The source of infection for genital herpes is the genital HSV-infected person. Subclinically infected or asymptomatic detoxifiers, patients with unrecognized symptoms or atypical genital herpes are the main infectious agents of genital herpes. Asymptomatic infections and intervals of recurrent genital herpes relapses can have asymptomatic detoxification, and their infectiousness is more dangerous.  3, the number of sexual partners, age of first intercourse and years of sexual activity, whether the cervix is protected or not, sexual orientation, frequency of sexual life, mode of intercourse and other sexual behavior factors are related to the spread and prevalence of genital herpes.  4, HSV infection of the genital skin mucosa is often latent in the sacral nerve root area, and this latent infection is the root cause of genital herpes recurrence. When there is HSV-1 infection in the mouth and lips first, even if genital HSV-2 infection occurs, the symptoms of the first episode are less severe and the likelihood of recurrence is less. Recurrent genitalia generally decreases in the number of episodes as the duration of the disease increases.  5, Humans have a natural susceptibility to HSV, but not everyone infected will develop typical genital herpes, the occurrence of genital herpes depends on both host and virus factors and can be manifested as latent infection, subclinical infection and typical genital herpes.  6, 80% of people with so-called subclinical HSV-2 infection are actually symptomatic, but the symptoms are only mild or atypical and ignored by the doctor or patient.  7. HSV can infect the fetus through the placenta (intrauterine HSV infection) and can also cause neonatal HSV infection. The risk of transmission of primary genital herpes to the fetus is considerably higher than that of recurrent genital, and this risk (transmission rate) is 20-50% and 0-8%, respectively.  8. Primary genital herpes in pregnant women is associated with spontaneous abortion, intrauterine growth retardation, preterm delivery, low birth weight and congenital HSV infection in infants, and even causes fetal death. Primary infection at different times of life leads to outcomes that are not entirely consistent. Recent studies have shown that recurrent genital herpes occurring during pregnancy is not associated with an abnormal outcome of pregnancy.  9, Serologic tests cannot distinguish between orofacial or genital infections.  10, The current main therapeutic drugs include acyclovir, famciclovir, and valacyclovir tablets. Asymptomatic or subclinical genital HSV infections generally do not require drug therapy.