Parkinson’s disease was first called tremor palsy when James Parkinson, a British physician, discovered that some people had the same condition, which was characterized by tremor of the limbs, muscle rigidity, motor slowing and abnormal posture and gait, and he defined it as “tremor palsy,” which was later changed to Parkinson’s disease in honor of the doctor who first described it. It was later changed to Parkinson’s disease in honor of the doctor who first described Parkinson’s disease. Today, Parkinson’s disease has been discovered for more than 200 years. It is now known that Parkinson’s disease is caused by degenerative lesions in the substantia nigra cells of the midbrain, resulting in a decrease in the secretion of a dopamine neurotransmitter needed to maintain normal physical activity, and thus the symptoms of Parkinson’s disease. However, exactly what causes the degenerative lesions in the nigrostriatal cells is not clear and is still under study. It is currently believed that the cause is more likely to be a combination of ageing, environmental toxins, and genetic susceptibility. Therefore, prevention can be advanced from these aspects. Since Parkinson’s disease is a chronic progressive movement disorder that gradually deprives patients of the ability to care for themselves, it is important to detect and treat it early. Nowadays, there are many advances and breakthroughs in treatment. There are more drugs, levodopa in the past, updated and replaced by methyldopa, Xanax, and Antan, with enhanced drug effects, except for many additional adjuvant drugs, Senfuro, Amantadine, Tysudar, Kotan, Ropinirole extended-release tablets, and Darinflex, which effectively control symptoms and slow down the progression of the disease. Surgical breakthroughs have had a great impact. In the past, disruption was used, which is a destructive surgery, irreversible and can only be done unilaterally, but patients with Parkinson’s disease basically have bilateral symptoms, so since the emergence of pacemaker surgery, disruption for Parkinson’s disease is gradually being eliminated. Pacemaker surgery is the abbreviation for deep brain electrical stimulation, which consists of stimulation electrodes, extension leads, pulse generators, and a programmable controller. Two stimulation electrodes are placed in specific nuclei of the brain, and the pulse generators are placed in the chest or under the armpit, and the extension leads are connected under the skin so that the entire set of materials is not visible. After the procedure, the pulse generator is switched on by means of a doctor’s programmable controller, and the parameters are adjusted to release a weak electrical current to the neurostimulator, which intervenes in the overexcitation of specific nuclei and brings a new balance to the neural circuit, thus effectively improving the symptoms of Parkinson’s disease, as well as motor complications (switching phenomenon, end-of-agent phenomenon, allodynia). The brain pacemaker procedure has the advantages of being minimally invasive, safe, reversible and adjustable, and evolvable. It is used for a long time, and after switching on, the patient’s symptoms can reach a steady state for a long time, and does not have peaks and valleys like taking medication. If the disease changes, the parameters can be reset and adjusted to reach a new equilibrium state as long as the pulse generator has power. If the pulse generator battery is exhausted, a new pulse generator is needed. Nowadays, there are rechargeable pulse generators with a lifetime of more than 10 years, and they have been included in rural cooperative medical care and employee medical insurance for the benefit of more people with Parkinson’s disease.