Scrotal dampness at night and fine during the day is usually considered to be related to physiological factors, but may also be due to pathological factors, such as eczema, urinary tract infection, prostatitis, etc. The actual condition of the patient requires targeted treatment under the guidance of a doctor. A, physiological factors such as tight underwear, as well as frequent masturbation, sexual life, can lead to an increase in scrotal temperature, resulting in increased water secretion near the scrotum, appearing at night scrotal dampness during the day is fine. Pay attention to personal hygiene, but also diligently bathe, change underwear, wear loose and breathable cotton underwear, reduce the number of sexual intercourse. Second, pathological factors 1, eczema: usually related to abnormal immune function, skin barrier dysfunction and environmental factors, endocrine disorders, etc. If eczema appears on the scrotum, it will lead to edematous swelling, crusting and cracking of the scrotal skin. As the blood circulation is faster during the day, it can inhibit the development of eczema, and at night when the blood circulation slows down and the metabolic capacity is weakened, there will be a situation where the scrotum is moist at night and fine during the day. Patients can use furnace glycolic lotion, boric acid solution, and glucocorticoids and other drugs for treatment under the guidance of a doctor; 2, prostatitis: caused by pathogenic bacteria infection, environmental factors, psychological factors, etc., can lead to abnormal secretion of the follicular glands in the scrotal area, coupled with a weaker metabolic capacity at night than during the day, there will be night scrotal humidity during the day nothing, may also be manifested as pain, abnormal urine, and accompanied by sexual dysfunction and mental and psychological symptoms. Patients should use drugs such as ciprofloxacin hydrochloride tablets and levofloxacin hydrochloride tablets for relief under the guidance of a doctor.