Tumor shrinkage after chemotherapy for squamous lung cancer is a sign that chemotherapy is effective. Chemotherapeutic drugs enter the blood circulation of human body through intravenous drip, and then reach the tumor cells in the lesion through blood circulation, affecting the growth and metabolism of the tumor cells, so as to kill the tumor cells. If the lesions of squamous lung cancer patients show shrinkage after chemotherapy, it means that squamous lung cancer patients are effective in chemotherapy and can continue to adopt this treatment. After chemotherapy, patients with squamous lung cancer should pay attention to strengthening nutrition, consuming more high protein and vitamin-rich food, taking light diet, avoiding spicy and stimulating food, and avoiding exertion. Chemotherapy may cause nausea, vomiting, bone marrow suppression, hair loss and other adverse reactions, patients should make corresponding psychological preparation, and should go to the hospital in time after the appearance of relevant chemotherapy side effects, doctors should treat the symptoms according to the patient’s symptoms to alleviate the patient’s symptoms.