Breast pain is the most common symptom of breast disease, and more than 50% of patients who visit a breast specialist do so because of breast pain. There are many causes of breast pain, and it is difficult to distinguish between different causes of breast pain in clinical practice. Therefore, at present, breast pain refers to a group of diseases that are manifested by pain in one or both breast tissues, with different pathogenesis and different treatment effects. According to the relationship between the onset of breast pain and menstrual cycle, breast pain can be roughly divided into two categories, about 2/3 of patients belong to cyclic breast pain and 1/3 of patients belong to non-cyclic breast pain. Periodic breast pain is most common in young and middle-aged women between the ages of 20 and 40, and may be caused by elevated estrogen levels in the body or hypersensitivity of breast tissue to estrogen. It manifests as a diffuse soreness or heaviness in both breasts, which may radiate to the armpits or upper arms, or may involve only one breast. Symptoms tend to worsen 3-14 days before menstruation and may be relieved to some extent with the onset of menstruation. In general, the pain is more severe in the outer upper quadrant of the breast than in other parts of the body, and in most patients breast pain disappears completely after menopause. Mild breast pain can occur in a considerable number of women in the premenstrual period, which is a normal physiological phenomenon and does not require treatment. However, if the pain is more severe, medication should be considered. There are two types of medications commonly used: herbal medicine and hormones. In Chinese medicine, premenstrual breast pain is associated with liver depression and spleen injury, blood stagnation and blood stasis, and treatment is mostly based on the principles of draining liver and Qi, activating blood circulation and dispersing phlegm. Most patients have some degree of relief of breast pain after taking these drugs, but the period of taking the drugs is longer. Hormonal drugs The main drugs are tamoxifen, danazol and bromocriptine, etc. Tamoxifen (triamcinolone) is very effective in reducing breast pain and works quickly, but hormonal drugs have potential side effects, such as endocrine disorders, menstrual disorders, and even increase the incidence of endometrial cancer, so they should be used with caution. The cause of non-cyclic breast pain is not clear, and the treatment is also more difficult. The current treatment drugs are mainly non-steroidal anti-inflammatory and analgesic drugs, such as fenbendazole, loxoprofen, etc. In conclusion, patients with breast pain should go to the hospital in a timely manner, first of all, to exclude malignant tumors or other diseases of the breast. In addition, choosing the right bra, eating a healthy and regular diet, getting a good sleep and having a peaceful mind are also beneficial to the natural relief of breast pain.