Most patients with hypertension have two peak periods of blood pressure between 6-8 a.m. and 5-7 p.m. This is the result of the body’s hormonal secretion. Due to the individual differences of each person, some patients have high blood pressure in the afternoon every day. In this case, it is recommended to go to the hospital to check 24-hour ambulatory blood pressure to understand the specific pattern of blood pressure changes with time, so as to facilitate the adjustment of antihypertensive medication. If you have oral antihypertensive drugs in the morning and your blood pressure is high in the afternoon, it means that the duration of antihypertensive drugs is not long enough or the dose of antihypertensive drugs is not enough, you can replace it with long-acting antihypertensive drugs, such as amlodipine and valsartan; or combine two antihypertensive drugs in the morning; or take a single tablet compound, such as combining amlodipine and valsartan; or take Irbesartan hydrochlorothiazide.