1.Skull base tumor surgery: Combining modern microsurgery technology, skull base surgery technology and minimally invasive neurosurgery concept, the treatment of skull base tumor reaches international advanced and domestic leading level. According to preliminary statistics, the anatomical preservation rate of facial nerve of this specialty group for auditory neuroma is over 90, and the functional preservation rate is over 75%. The total resection rate (Simpson grade I and II) of skull base meningioma in pterygoid crest, saddle area, rock bone, slope and occipital foramen is more than 89%, and more than 95% of patients have good quality of life treatment after surgery. In recent years, based on microanatomy and microsurgery techniques, and with international first-class surgical equipment such as intraoperative magnetic resonance, three-dimensional virtual imaging preoperative planning system, and neuroelectrophysiological detection system, we have introduced the concept of minimally invasive surgery into difficult skull base surgeries such as cavernous sinus, rock bone – slope area, and jugular foramen area, realizing the individualization of treatment and the transformation from simple tumor resection to tumor resection and function preservation. It has realized the transformation from simple tumor resection to tumor resection and function preservation. East 2, pituitary tumor, craniopharyngioma, pineal tumor and other neuroendocrine tumors: In recent years, our team has implemented the concept of minimally invasive neurosurgery into the whole process of treatment of these tumors. At the same time, with the strong technical support from the endocrinology, radiotherapy and obstetrics and gynecology departments of the general hospital, the patients can maintain their normal physical development and reproductive functions. 3.Surgical treatment of ischemic cerebrovascular disease: Surgical treatment of ischemic cerebrovascular disease is one of the key research directions of this specialty group. Internal carotid artery endothelial dissection is the international gold standard surgery for the treatment of internal carotid artery stenosis, but the development in China is relatively lagging; intracranial and extracranial vascular bypass surgery for the treatment of ischemic cerebrovascular disease has experienced a high point – low point – revival in the international arena, and with the publication of several groups of high-quality evidence-based medical evidence in recent years, intracranial and extracranial vascular bypass surgery for the treatment of ischemic cerebrovascular disease has again become a hot spot in neurological research, and its The key lies in the indications for surgery and the choice of surgical approach. 4.Complex tumors involving intracranial venous sinuses and important drainage veins: We are the first in China to fuse functional magnetic resonance (MR) and magnetic resonance cerebral venous angiography (MRV) and apply them to the intraoperative navigation system, and combine them with venous sinus reconstruction technology, so that the total incision rate and safety of paraneoplastic meningioma reach the international advanced level. Based on anatomical research, we proposed different surgical approaches such as suboccipital transcallosal (Poppen approach), subscallosal superior cerebellar approach (Krause approach), and posterior longitudinal fissure according to the relationship between the tumor and the veins and arachnoid, and achieved good clinical results. The results have been good. 5. Visual and auditory pathway-related intracranial tumors: Visual-related intracranial tumors include pituitary tumors, craniopharyngioma, meningioma, chordoma, cholesteatoma, glioma, etc.; auditory-related tumors include auditory neuroma, meningioma, cholesteatoma, etc.. These intracranial tumors are often located in important functional areas and can be quite tricky to diagnose and treat. Visual and auditory related intracranial tumors are one of the key research directions of the Minimally Invasive and Skull Base Surgery Group, which strives to preserve the neurological function of patients while total resection of tumors, so that patients can obtain good social adaptability. 6.Cranial base vascular surgery: We have carried out various skull base access and high-flow intracranial bypass techniques to treat complex aneurysms in cavernous sinus, ophthalmic artery, pars plana, vertebral artery, basilar artery, etc. earlier in China. Intracerebroventricular tumor surgery: Intraoperative magnetic resonance, functional magnetic resonance navigation, brain fiber bundle navigation and intraoperative neurophysiological detection are used to select the best surgical approach to avoid damage to visual, language and higher cognitive functions. For tumors in the four ventricles, the cerebellar medullary fissure approach is used to remove the tumor using natural anatomical channels, which significantly reduces the patient’s postoperative ataxic dysfunction. 8. Tumors in the functional brain area: We have built a world-class minimally invasive neurosurgical platform for the functional brain area, using conventional MRI, BOLD-fMRI, DTI, MRS, intraoperative Doppler, multi-image fusion mode functional neurological navigation, etc. to develop a minimally invasive neurosurgical plan to achieve a minimally invasive neurosurgical plan. Surgical planning to achieve individualized and intelligent features of minimally invasive neurosurgery. Using intraoperative MRI to update navigation data in real time during surgery, integrating cerebral blood flow, intraoperative neurophysiological monitoring technology and direct electrical stimulation of functional areas, establishing an early warning system for brain function monitoring and protection, and timely updating the surgical plan to achieve the goal of maximum lesion removal and minimum damage to neurological function. 9.Cranial nerve disease: In China, we applied the lock-hole approach to treat trigeminal neuralgia, glossopharyngeal neuralgia and facial muscle spasm earlier, and completed the surgical procedure through a large coin incision, which greatly reduced the hospitalization time, treatment cost, surgical pain and postoperative complications. Our statistics show that the efficiency of trigeminal neuralgia in this group is 97%, which is higher than the international general standard. The facial nerve-sublingual nerve anastomosis was used to treat peripheral facial palsy, and different surgical procedures were adopted according to the condition of the sublingual nerve during the operation, which not only restored the function of the facial nerve but also minimized the damage to the sublingual nerve. 10.We are the first in China to apply bony decompression plus dural wall peeling for the treatment of cerebellar subm tonsillar herniation and spinal cord cavity (Chiari malformation), which fundamentally eliminates a series of complications caused by the need to open the dura in the previous surgery, and the surgical reaction is mild and has achieved good results. For complex craniocervical junction deformities, different methods of decompression and fixation are used depending on the source of compression, allowing individualized and minimally invasive treatment of this recognized difficult condition.