Cerebrospinal fluid rhinorrhea is a disease in which cerebrospinal fluid enters the nasal cavity or sinuses from physiological or pathological gaps or defects in the skull due to rupture of the meninges, often secondary to intracranial infection and life-threatening. If there is bloody fluid flowing from the nostril at the time of trauma and the center of its trace is red while the periphery is clear, or if the colorless fluid flowing from the nostril is not crusty after drying, cerebrospinal fluid rhinorrhea should be thought of. If the fluid flowing from the nostril is clear and colorless and characterized by increased flow under low head pressure and compression of the jugular vein, the possibility of cerebrospinal fluid nasal leakage is suggested. The final diagnosis relies on quantitative glucose analysis, i.e., cerebrospinal fluid containing more than 30 mg% glucose. Treatment of cerebrospinal fluid nasal leakage includes both non-surgical and surgical treatment. Non-surgical treatment includes measures to lower intracranial pressure and reduce the amount of cerebrospinal fluid leakage to promote healing of the cerebrospinal fluid fistula. It is generally accepted that cerebrospinal fluid leaks caused by skull base fractures should be considered for surgical treatment if the leak is still present 2 to 4 weeks after non-surgical treatment. Cerebrospinal fluid nasal leakage used to be treated by neurosurgery with craniotomy, which has a success rate of about 60%, and is not easily accepted by patients because it is not only traumatic but also causes permanent loss of smell after surgery. In recent years, the development of nasal endoscopy technology has expanded the scope to the field of nasal neurosurgery. The endoscopic transnasal approach to repair cerebrospinal fluid nasal leak has the advantages of minimally invasive surgery, preservation of function, clear visualization, and direct vision, which is becoming more and more popular among scholars and patients. The key to successful endoscopic transnasal cerebrospinal fluid rhinorrhea repair is accurate localization of the fistula, accurate sealing of the fistula and selection of the appropriate repair material. For septoparietal and septal sinus cerebrospinal fluid leaks, a transmedial approach is used; for cerebrospinal fluid nasal leaks from the pterygoid sinus, an approach between the middle turbinate and the nasal septum (paranasal septum) is used, and the fistula repair technique: local granulation tissue is excised and the bony normal dural margin around the fistula is enlarged. Free fascia, mucosa of the middle turbinate, muscle and adipose tissue are used to repair the leak. Therefore, nasal endoscopic repair is the preferred means of surgical treatment for cerebrospinal fluid nasal leaks.