Clustered breast calcifications have a 30-50% chance of being malignant and may also be benign lesions such as intraductal papillomas. Clustered breast calcifications are relatively few calcifications occupying a small volume of breast tissue. There should usually be at least 5 foci of calcification within a 1 cm area, and they should not be more than 2 cm in extent. There is about a 30-50% chance that the clustered calcification is a breast malignancy such as breast cancer, which may be caused by necrotic debris from cancer cells, secretions from cancer cells, and other causes of calcification. There is also a greater likelihood that clustered calcifications are the result of benign lesions such as breast cysts, fibromas, and intraductal papillomas, which may be related to active secretion of mammary cells and deposition of calcium salts. Cluster calcification of the breast is a description of the distribution of calcification in the breast. Generally speaking, breast calcification needs to be combined with morphology and density to determine the possibility of benign or malignant. Patients are advised to consult a specialist with the report and follow the doctor’s instructions for further examination and treatment.