Microalbuminuria is an early sign of kidney damage in “fat people” (we call it metabolic syndrome) characterized by obesity, hyperglycemia, hyperlipidemia, and hypertension, and “early” means early detection and timely intervention to prevent Early” means that early detection and timely intervention can prevent the progression of the disease. Unfortunately, because the clinical symptoms are not obvious when microalbuminuria occurs, most people just feel like they have a “general belly” and find more foam in their urine. Therefore, many patients are paralyzed by this, resulting in delayed diagnosis and treatment of the disease, harming health. General belly: only control “three high” is not enough High blood pressure, hyperglycemia, hyperlipidemia is a common factor causing microalbuminuria, and as the pathological basis of metabolic syndrome – insulin resistance is also one of the important factors affecting kidney function, if only to control If only the “three highs” are controlled and the treatment of insulin resistance is neglected, there will still be a risk of kidney damage. Generally speaking, hypertension, hyperglycemia and hyperlipidemia will attract attention and be treated. However, obesity, especially central obesity (male: waist circumference ≥ 90 cm or waist-to-hip ratio ≥ 0.9; female: waist circumference ≥ 85 cm or waist-to-hip ratio ≥ 0.85) is often overlooked, while central obesity is precisely an important cause of microalbuminuria. Central obese people often have insulin resistance and hyperinsulinemia, which can damage renal function by affecting renal hemodynamics and renin-angiotensin-aldosterone system, damaging vascular endothelial cells, interfering with fibrinolytic system and releasing a lot of inflammatory factors, leading to proteinuria. We found in the clinic that many patients with metabolic syndrome like Mr. Chen, despite the control of blood pressure, blood glucose and lipids, have no significant decrease in weight waist circumference and high fasting insulin, which are the manifestations of uncorrected insulin resistance, and thus microalbuminuria is not reduced, and it is very important to treat central obesity and improve insulin resistance at this time. Chinese medicine insulin sensitization: promising application According to Chinese medicine, patients with metabolic syndrome are mostly due to “Qi deficiency without transformation”, which leads to the failure of normal distribution of essence and microscopic substances. Therefore, under the premise of basic treatment such as behavioral intervention, blood pressure, blood glucose and lipid control, we adopt the “Yi Qi Dispersion and Aggregation Method” as the main treatment, plus the use of Chinese herbs to clear heat and consolidate the kidney and detoxify and remove turbidity, such as Astragalus, Huang Lian, Pu Huang, Ze Xie, mung bean paste and Perilla leaf to form the Yi Qi Dispersion and Aggregation Detoxification Formula to treat microalbuminuria, which has achieved remarkable efficacy. Studies have confirmed that Yi Qi San Ju Detoxification Formula has obvious effects of insulin sensitization and inhibition of inflammatory response, clearing insulin resistance, the upstream root cause of microalbuminuria production, and combining with antihypertensive, hypoglycemic and lipid-lowering drugs to prevent the occurrence of microalbuminuria from different aspects, reducing the risk of kidney damage in patients. Since insulin resistance can also cause disorders of glucose metabolism and lipid metabolism, this treatment also helps to improve glucose and lipid metabolism, reduce vascular endothelial damage and play a role in protecting the cardiovascular system. Under physiological conditions, the albumin in human urine is extremely small, not exceeding 20 mg/l. If the protein content in the urine is 20-200 mg/liter, it is considered microalbuminuria. At this time, the kidney lesion can still be reversed through active treatment. Once the albumin content in the urine exceeds 200 mg/l, the urinary protein characterization is often positive, indicating that the kidney damage is already very serious, and it is more difficult to reverse it.