1.Identify the cause and mechanism of chronic nephritis proteinuria belongs to the category of “stone water”, “deficiency labor”, and “external drainage of essence” in Chinese medicine, and the root cause is positive deficiency and evil reality. The main cause of deficiency is weakness of the spleen and kidneys, while the main cause of evil is external sensation, water-dampness, damp-heat and blood stasis. According to the theory of Chinese medicine, kidney is the water organ, which is the origin of the first heaven, harboring the true yin and containing the vital yang, and receiving the essence of the five viscera and six bowels, while spleen is the yin earth, which is the origin of the second heaven, transporting the essence of water and grain to cultivate and nourish the essence of the kidney, and also has its own role of regulating and raising the clear and lowering the turbidity. Deficiency of the kidneys and failure of storage, deficiency of the spleen and failure of the spleen to transport, and failure of the clear yang to rise, can lead to loss of distribution of essence, and proteinuria due to downward leakage of essence. The pathological changes of the kidney lesions caused by the actual evil are summarized into four types: loss of lung circulation and purification, internal stagnation of water-dampness, internal obstruction of damp-heat, and obstruction of blood stasis. If external evil is felt, the lung becomes congested, the lung loses its propagation and purification, the three jiao are not properly regulated, and the water and grain essence cannot return to their proper channels, resulting in the leakage of essence; water-damp and damp-heat evil can trap the middle jiao, resulting in the spleen not ascending to the clear and the clear and turbid down, and the damp-heat evil often stays in the lower jiao, resulting in the bladder losing its contract and the leakage of essence; stasis of blood is also a common cause and pathological manifestation of kidney disease, which is stasis at the beginning of the disease, and also stasis after a long period of time, stasis of blood, stagnation of the kidney ligaments, obstruction of qi-transformation The stagnation of blood and stagnation of kidney ligaments, stagnation of qi and chemistry, loss of essence, and therefore clinical symptoms. 2. The use of drug pairs is a combination of the opposite or complementary medicinal properties and functions of drugs to complement each other’s strengths and weaknesses to achieve the best therapeutic effect. Earlier related discussions can be found in “Nei Jing” and “Treatise on Typhoid”, while monographs include “Lei Gong’s Medicine Pairs” and “New Wide Medicine Pairs”. On the basis of the diagnosis and treatment, the medicine pair is used to manage the complexity with simplicity, which can achieve the miraculous effect of “making it harmonious and peaceful”. (1) Astragalus with Huaiyanyang to strengthen the spleen and consolidate the essence Astragalus is warm in nature and slightly sweet in taste, it can strengthen the spleen and benefit the qi, raise the yang and consolidate the surface, promote water and reduce swelling; Huaiyanyang is flat and sweet in taste, it can nourish the yin and benefit dampness, smooth and astringent, it can nourish the kidney and nourish the spleen and stomach. In the ancient formula, the two medicines are used together to nourish the true yin while replenishing the vital energy, and the yang rises while the yin responds to the effect. The treatment of chronic nephritis proteinuria with Astragalus with Huaiwu yam is mainly to strengthen the role of strengthening the spleen and replenishing the qi. As the saying goes, “the atmosphere of a person is vigorous, it can absorb the whole body’s gasification without making it sink”. The spleen is the source of Qi and blood biochemistry. If the spleen is deficient in transporting the clear yang, the grain will flow down and the essence will leak out. The spleen can be tonified to transport the water and grain, raise the clear and lower the turbidity, so that the lung qi can be unified and controlled, and the kidney qi can be enriched to hide the dormant. Therefore, treating the spleen becomes an important part of regulating the three jiao and controlling the leakage of essence and microorganisms. Astragalus in combination with yam is to take its effect of both spleen and kidney tonicity and essence collection. Clinically, if you see the symptoms of sunken middle qi, then add the ascending medicine such as Radix et Rhizoma Ginseng, Atractylodes Macrocephala, Radix Bupleurum, etc.; if you see the symptoms of kidney deficiency, then add the warming and astringent kidney products such as Golden Cherry, Cornu Cervi Pantotrichum, Bacopa Monniera, etc. (2) Thatch root with Biyu san Clearing damp-heat White thatch root is sweet in taste, cool in nature, hollow and articulated, so it can dispel real fire; it has twelve small holes around it, just like the twelve meridians of human beings, so it can ventilate the internal organs and smooth the meridians, treating heat of external sensation and benefitting the water around the body; on the other hand, it is light in taste and exquisite in body, so it is good at relieving dripping and astringency of urine; “Medicine Zhongzhong Ginseng and Xilu” uses white thatch root soup to treat retention of urine, which is caused by yin deficiency that cannot transform yang, so the urine is unfavorable, or there is It is also used to treat the symptoms of dampness and heat congestion, resulting in unfavorable urination and accumulation of edema. It is said to have been created by one of the Four Great Masters of the Jin Dynasty, Liu Heshan. The symptoms treated by “Liuyi San” can be summarized in four words: heat, thirst, gonorrhea and diarrhea, and Liuyu San can also treat red eyes and sore throat, and sores on the tongue. Not only gonorrhea, but also the pathological development of chronic nephritis has “kidney deficiency and bladder heat”, so the existence of damp-heat cannot be denied because of deficiency. (3) Dan Shen with Gui Gong (3) Danshen with Ghostly feather, blood circulation, blood circulation, blood circulation, blood circulation, blood circulation, blood circulation, blood circulation, blood circulation. Modern experiments have shown that Danshen can inhibit glomerular inflammation and immune response; Danshen is sweet and slightly bitter in taste, which can activate blood circulation and dispel blood stasis, cool blood and eliminate carbuncles, and remove annoyance and tranquilize the mind, as stated in “Women’s Ming Theory”, “a single taste of Danshen has the same function as four things”. In recent years, it has been found that the disorder of blood clotting mechanism plays a decisive role in the occurrence, development, regression and prognosis of glomerular diseases, and the hypercoagulable state is blood stasis, and blood stasis is present in all types and stages of the disease. Therefore, the clinical treatment of proteinuria in chronic nephritis should be based on the identification and treatment of blood stasis. The two are suitable for all kinds of blood stasis or blood stasis with heat, which can be used to activate blood circulation without leaving stasis. However, it should be used with caution, and patients with bleeding or bleeding tendency should use it with caution. (4) Zeilan with maize beard to resolve blood stasis and promote water circulation Zeilan is mildly warm, bitter and pungent, with the function of activating blood circulation and resolving blood stasis, promoting water circulation and reducing swelling; maize beard is mild and sweet, and has been used by folklore since ancient times for the treatment of diabetes and hypertension, with the effects of diuretic, heat relief, calming the liver, and promoting bile. Chronic nephritis, long-term protein loss, more complicated edema, “water is the most yin, its essence in the body, water only fear of earth, its control in the spleen”, medical treatment is often used to warm the spleen and kidney and regulate the water channels of the three jiao method. If edema does not subside for a long time and treatment from the lungs, spleen and kidneys has no effect, blood activators can be used in combination with water-relieving drugs. As the saying goes, “blood is water when it is not favorable” and “water can cause disease to blood and blood can cause disease to water”. Edema that is ineffective in treatment of qi component is caused by internal obstruction of blood stasis in prolonged illness, so it should be sought in blood component. Ze Lan invigorates Blood and moves water, together with Cornus officinalis, it is suitable for patients with kidney disease who have long-standing illnesses with swelling and stasis.