After Eisenmenger’s syndrome due to pulmonary hypertension, the patient is not suitable for surgery. If a conventional surgery like repairing the defect is done, it will cut off the patient’s pulmonary hypertension causing the patient’s blood to pass from the pulmonary artery, and the right to left shunt from the original defect to relieve the right heart pressure retreat, which will accelerate the speed of the patient’s heart failure leading to death and is a contraindication to surgery. Not to do conventional surgery this part of the patient is not hopeless life, many of these patients can survive 10 years or even 20 years, of course, due to advanced cyanosis hypoxia, right heart insufficiency, to affect the quality of life, but this is a chronic process, patients can engage in light work, can get married, male patients can give birth. Although heart-lung transplantation can theoretically treat such patients, it is rarely carried out in China and not many abroad, and is expensive after surgery. The drugs used to lower pulmonary artery pressure are limited in their effect, and there is no need to place great hope in them. If right heart failure manifestations such as edema and organ stasis occur in the late stage, symptomatic medications can be used to alleviate the progression of the disease.