Many people are afraid of Parkinson’s disease, which many call “the cancer that never dies”. Parkinson’s disease is a chronic disease, and the treatment process is very long and involves daily medication, while the comprehensive treatment of Parkinson’s disease includes medication, pacemaker surgery and rehabilitation. Surgery is a pacemaker procedure that allows Parkinson’s patients to take care of themselves in their daily lives and regain their lives. Is surgery suitable for all patients with Parkinson’s disease? What is the surgical procedure? 1. How do I know if I am suitable for surgery? First, the diagnosis of primary Parkinson’s disease, excluding secondary Parkinson’s disease and Parkinson’s superimposed syndrome, etc. Second, once the medication is effective, but now the effect of medication gradually becomes worse. Third, the examination did not have serious mental and cognitive impairment, etc. Fourth, the patient and his family interpreted and expected the surgery correctly and were able to cooperate with the treatment. Fifth, there are no other major diseases, which will be examined in detail after admission and evaluated according to the examination results. 2.The principle and process of surgical treatment? Surgery is to improve the abnormal neural electrical activity by stimulating the relevant nuclei with microcurrent, thus effectively controlling and improving the symptoms of Parkinson’s disease. However, surgery cannot stop the slow progression of the disease, and as the disease develops and changes, patients can come to the hospital in time for program-controlled parameter adjustment to continue to effectively control the symptoms. First, primary Parkinson’s disease will be diagnosed, mental and cognitive exams, physical exams, and a methyldopa shock test will be done. Based on all the tests, the patient will be evaluated to see if surgery is possible, and if so, a surgery schedule and surgical plan will be arranged. If not, the patient will be treated with medication and conditioning, etc. During the surgery, the head frame is installed, MRI is done, stereotactic localization calculation is performed, the operating room is entered, the implantation of the stimulation electrodes on the determined position, the patient’s limb response is observed, trembling, stiffness, motor retardation control, whether the movement of arms and legs is flexible, this session is local anesthesia, the patient is conscious and conscious, questions are asked whether the patient has not feeling, etc. Intraoperative test is good, the patient has no discomfort, proceed to the next step, connect the wire and neurostimulator (battery), after everything is done in the operation, return to the ward, give nutritional support treatment. Generally one month of recovery comes to the hospital for brain pacemaker on and off regulation, combined with medication adjustment and rehabilitation exercises to better improve the symptoms and improve the patient’s quality of life. More than 150,000 people have been implanted with pacemakers worldwide. The quality of life of patients with Parkinson’s disease has been improved by surgical treatment. Surgical treatment has become a new hope for Parkinson’s disease patients.