(Disclaimer: This article is only for scientific purposes, in order to protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: 45-year-old male, used to have a fatty liver, the last 3 years a lot of alcohol, in the past half a month, fatigue, loss of appetite, yellow urine, abdominal distension symptoms progressively aggravated, according to the gastritis given to the oral medicine, the therapeutic effect was poor. And the above symptoms aggravated significantly, abdominal distension with lower limb edema to our hospital for further examination, confirmed the diagnosis of alcoholic cirrhosis with primary peritonitis, peritoneal effusion, given standardized treatment, the patient’s fatigue, abdominal distension, double lower limb edema symptoms disappeared, liver function transaminases return to normal. [Basic information] Male, 45 years old [Disease type] Alcoholic cirrhosis with primary peritonitis, peritoneal effusion [Hospital] No. 988 Hospital of the PLA Joint Command and Security Forces [Time of consultation] February 2019 [Treatment plan] Drug treatment (magnesium isoglycyrrhizinate injection + gardenia jasmine yellow injection + compound turtle turtle turtle soft liver tablets + eszopiclone tablets + injectable naloxone hydrochloride + injectable cefuzodoxime sodium + spironolactone tablets + furosemide tablets). (Treatment cycle] 16 days of hospitalization, 4 weeks after the review [Treatment effect] the condition has been controlled, the indicators have recovered, symptomatic relief I. Initial interview Patient male, 45 years old, drinking alcohol all day long, with alcohol as a companion, in the past half a month to eat more and more less, his mother found that the patient wasting obviously, given to take medication after the appetite does not improve, in recent days found that the abdominal distension is obvious, accompanied by edema of the lower limbs The patient was diagnosed with liver cirrhosis and ascites on outpatient examination and was admitted to the department. Hepatitis B five tests were negative for hepatitis A and C antibodies, negative for hepatitis B surface antigen antibodies, and abdominal ultrasound showed enlarged liver, splenomegaly, and ascites. Liver elasticity scan showed cirrhosis and fatty liver. Based on the patient’s medical history, symptoms and signs, the current diagnosis was: alcoholic cirrhosis with primary peritonitis and peritoneal effusion. Second, the treatment process After the patient’s clinical diagnosis is clear, positively give isoglycyrrhizic acid magnesium injection, Yin gardenia yellow injection intravenous injection, protect the liver and reduce the yellow, give the compound turtle shell soft liver tablets oral anti-hepatic fibrosis treatment. Because the patient’s alcohol withdrawal symptoms were obvious, eszopiclone tablets were given orally, while naloxone hydrochloride injection was given intravenously to wake up the brain. In order to prevent disulfiram reaction, cefazodime sodium for injection was given 3 days after alcohol withdrawal for anti-infection, and oral spironolactone tablets and furosemide tablets were given for diuretic treatment. Third, treatment effect The patient’s discomfort symptoms gradually improved, the general condition obviously improved, appetite gradually increased, and the symptoms of fatigue improved. After 2 weeks of hospitalization, liver function improved significantly, renal function and blood routine were not abnormal, abdominal ultrasound examination, ascites decreased significantly, continue to strengthen the comprehensive treatment. After 16 days of hospitalization, the patient’s condition was clinically cured and he was discharged home, and was instructed to continue to take the above medications orally for 4 weeks. The patient and his family were worried about the recurrence of the disease, and they told the patient that he had to have a strong willpower, could not get involved in alcohol again, and continued to strengthen the comprehensive treatment, and the cirrhosis could be reversed. 4 weeks later, the patient came to the hospital for a review, and said that he had not consumed alcohol again, and had a regular life style and routine, and the patient’s mental and physical strength had returned to normal. Note: We are glad that the patient has recovered after treatment, but we still need to advise the patient to pay attention to rest in daily life, avoid prolonged staying up late or overwork, pay attention to strengthening nutrition, mainly vitamin-rich and protein-rich food, avoid drinking again, and avoid spicy and cold food; at the same time, pay attention to participate in physical exercise to enhance their physical fitness. If there are uncomfortable symptoms, we should consult a doctor in time. Fifth, personal feelings This patient due to long-term heavy drinking, caused by alcoholic cirrhosis, but fortunately the patient’s family in time to send the patient to the hospital, after a series of standardized treatment, the patient’s condition has finally been effectively alleviated. Therefore, we sincerely advise the people to avoid drinking a lot of alcohol in daily life, especially for those with poor liver function, they should stay away from alcohol and cherish their lives.