Progesterone currently used generally does not affect the growth and development of the fetus, but there may be side effects, the main side effects are the following: 1, progesterone has the effect of dilation of intracranial blood vessels, easily cause dizziness, headache, sleep disorders; 2, progesterone can cause nausea, vomiting, abdominal distension or constipation and other gastrointestinal reactions; 3, under the guidance of doctors to use the appropriate amount of progesterone, generally no fetal The first trimester of pregnancy is an important period for the growth and development of the fetus, so the medication must be used under the guidance of a doctor in the early stages of pregnancy, and should be stopped in time after the condition is relieved. In addition, overdose of progesterone may lead to excessive progesterone in the fetus, which may result in excessive progesterone in the baby after birth, leading to feminization of the boy or premature sexual maturity. Progesterone needs to pay attention to the following points: 1, pay attention to the adverse drug reactions, some people may experience nausea, vomiting, dizziness, etc., it is recommended to take the drug half an hour after the morning meal; 2, oral progesterone in the process of increased vaginal bleeding, abdominal pain does not ease or even worsen, it is recommended to follow up with the hospital in a timely manner; 3, diabetes, cardiovascular disease, as well as serious liver and kidney function damage is contraindicated.