Malignant tumors are one of the overwhelmingly incurable diseases that no one wants to face. Choosing a treatment option is a very difficult decision for patients and their families. Hopefully, this article will provide you with a little help. At present, the means and methods of treatment are limited, and most of the advanced tumors are incurable. Most of the advanced tumors are incurable, and the financial capacity of each family is different. I would like to state my personal opinion only. For tumors that can be cured by existing technology (early stage tumors, lymphoma, germ cell tumors, nasopharyngeal carcinoma, etc.), we should try our best to help patients to build up their confidence, overcome the difficulties, and try our best to get cured. More common are incurable tumors, how much should be invested in treatment and how to go about it, and there are many different opinions. In my personal opinion, the best treatment is the one that makes the patient and his/her family feel the greatest happiness. A few common questions are as follows: 1. When the patient’s state of consciousness is clear and his personality is sound, should the patient be truthfully informed of his condition? 2.When the patient asks for treatment, under what circumstances can the physician and the family refuse, and how to face after the refusal? 3.When the patient asks to give up, what kind of situation can the physician and family members support the patient to give up, and what kind of situation should be persuaded? 4, when the patient loses consciousness, should we choose to give up or active treatment? In the following articles to answer one by one.