Diabetic patients feeling cold hands and feet may be the manifestation of diabetes-induced circulatory disorders of the blood vessels at the ends of the limbs. If patients are not actively treated, diabetic neuropathy, diabetic foot and other consequences may occur; in serious cases, gangrene may even occur. 1. Diabetic neuropathy: cold hands and feet of diabetic patients may suggest that the blood circulation at the end of the limbs is poor, and the blood can’t normally nourish the peripheral nerves; if the blood glucose is not effectively controlled for a long time, the damage to the peripheral nerves may be even more serious, which may lead to numbness, ants and pins and needles in hands and feet, which is limited to the hands and feet at the beginning, and may develop upward and involve other organs and systems in the long run. 2. Diabetic foot: Diabetes-induced circulatory disorders at the end of the limbs will begin to show cold hands and feet, and over time, the blood vessels and nerves in the feet far from the ankle joints will become diseased, resulting in insufficient blood supply to the feet, abnormal sensation, and ulceration, infection, and other symptoms, and in severe cases, it can affect the muscles and bones, leading to tissue necrosis or even amputation. In addition, environmental factors (such as sudden drop in temperature, contact with cold things, etc.) may also cause patients with cold hands and feet. It is recommended that patients go to the endocrinology department of regular hospitals in a timely manner, and with the help of professional doctors, choose the appropriate treatment plan and actively control blood sugar to avoid delaying the condition.