As the Chinese New Year approaches, there are more and more meals and parties, and the rate of drunkenness is getting higher and higher. According to incomplete statistics, since January, the number of patients seeking medical treatment for drunkenness in hospitals is significantly higher than that of the same period last month by more than 20%, with more than 30 patients every day. Especially in the emergency room at night, all kinds of symptoms are present, and serious ones even appear coma. It is understood that the number of patients with digestive, kidney, liver and even urinary system diseases caused by drunkenness is also increasing in the hospital’s inpatient department. The wine, which is known as “jade jelly” by literati and writers, is hurting every organ of the human body, so that people are tossed into hospitals? What is it that makes people behave differently when they are drunk? Why do so many people go to the tiger mountain when they know there is a tiger in the mountain? How can we minimize the harm of drunkenness? How does alcohol harm us? The stomach is thus taken off the condom by alcohol. Director Jin Xiaojing told reporters that drinking a lot of alcohol will first have a negative impact on the digestive system. After entering the body, alcohol first enters the digestive tract, stimulating the mucous membrane of the mouth, esophagus and stomach, causing a burning sensation. This is because alcohol will dissolve the gastric mucosa cells, so that the stomach loses its protective layer, if a lot of alcohol, causing damage to the gastric mucosa, which is often accompanied by stomach pain, vomiting, indigestion, serious gastric bleeding, black stool or vomiting coffee-like bloody stomach contents, if the amount of bleeding and rescue is not timely, shock and even death will occur. Some experts have autopsied a number of corpses died due to drunkenness and found that the internal organs of all the deceased were extensively congested, especially the stomach and duodenum mucous membrane congestion, edema and bleeding is more serious, and the gastric mucosa of severe cases also have partial necrosis. All this damage is determined by the concentration of alcohol in the stomach, at 10% concentration can stimulate gastric juice secretion; 20% concentration, the gastric acid secretion and gastric peristalsis is inhibited; 40% or more, it is easy to occur acute gastritis, gastric ulcer, acute pancreatitis. Alcohol liver is no longer the liver The liver is the only organ of ethanol (alcohol) metabolism, 80%-90% of the causes of cirrhosis of the liver is caused by alcohol consumption. So how does alcohol destroy the liver? After a person drinks alcohol, more than 90% of the ethanol is broken down and metabolized in the liver. So what are the products of the breakdown and metabolism of ethanol? First, ethanol is catalyzed by the enzyme ethanol dehydrogenase in the hepatocyte plasma and eventually becomes carbon dioxide. Second, ethanol is oxidized to acetaldehyde by the ethanol oxidation system in the hepatocyte microsomes. Acetaldehyde is a very active chemical that is toxic in many ways. Its toxicity to the liver is manifested in: first, it decreases the oxidation of fatty acids by the liver, leading to swelling and even collapse of liver cells. Secondly, it has an interfering effect on amino acids, causing damage to liver cell membranes. It can also lead to the formation of fatty liver due to the disturbance of fatty acid metabolism in the liver caused by acetaldehyde. In addition, acetaldehyde toxicity degenerates hepatocytes, causing humoral and cellular immunity production, resulting in immune manipulation of hepatocytes, leading to the development of alcoholic hepatitis. Finally, prolonged heavy drinking almost inevitably leads to cirrhosis of the liver, where the diseased liver no longer processes the nutrients from the digestive tract and is unable to process the drugs ingested into the body, and the life of the person is in jeopardy. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. At the same time, due to the long-term existence of the above-mentioned conditions, the immune function of the gland is impaired, and it is easy to cause infection by pathogenic microorganisms such as bacteria, and bacterial inflammation occurs. Excessive alcohol consumption can lead to kidney failure Drinking alcohol affects the nitrogen balance of the body, increases the breakdown of proteins and increases the urea nitrogen content in the blood, which inevitably increases the burden on the kidneys. Although 90% of the absorbed alcohol is metabolized and decomposed in the liver and 10% is eliminated by the kidneys and lungs, it seems that the damage of alcohol to the kidneys is not as prominent as its damage to the liver and other organs, but the damage to other organs can lead to kidney damage and even kidney failure. For example, alcoholic pancreatitis, especially acute necrotizing alcoholic pancreatitis is a common critical clinical condition, which can lead to multiple organ insufficiency syndrome with acute renal failure as the disease progresses, with high mortality.