Total knee replacement is usually indicated for patients over 60 years of age with severe arthritis, but is also used in adults as a last resort. Artificial joint replacement can be used not only for osteoarthritis, but also for traumatic arthritis, rheumatoid arthritis and other non-suppurative joint pathologies, but not every patient is a candidate for this procedure. Generally, patients over 60 years of age with knee pain, more severe joint dysfunction, and who have failed to respond to medications and other conservative treatments may consider knee replacement. The specific condition of each patient is different, but patients with the following conditions can be considered for knee replacement: 1. Osteoarthritis of the knee or other arthritis; 2. Knee pain, with poor results of conservative treatment for more than half a year; 3. Knee pain every day, which not only affects the work but also hinders daily activities, such as climbing stairs and getting off the bus with knee pain. Because of knee pain, can not walk more than 200 meters, can not sleep at night; 4, knee joints have obvious instability playing soft legs; 5, knee joints have obvious deformity, roped legs or X-shaped legs; 6, certain serious knee fractures, can not be reset and fixed; 7, tumors around the knee joints; 8, knee joints have been replaced after the prosthesis loosening.