What are the current treatments for pituitary adenomas?

       Surgery is the first choice (for most pituitary adenoma cases), and emergency surgery should be performed in cases of pituitary stroke (referring to symptomatic pituitary hemorrhage or infarction) or hydrocephalus.  There are usually two types of surgery: craniotomy and transsphenoidal sinus approach, of which craniotomy is less commonly used and only a few complex cases are suitable for this type of surgery. Transnasal-pterygoid sinus approach pituitary adenoma resection has been widely adopted internationally, and most patients are suitable for this procedure, which has the advantages of less trauma and better outcome.  Note that not all pituitary adenomas need to be operated, some of them can be treated with medication; some do not necessarily need to be treated, but can be observed for a long time, and decisions need to be made under the consultation and guidance of experienced doctors.  2.Stereotactic radiosurgery treatment Those without intracranial pressure increase sign and tumor diameter <2cm can consider γ-knife or X-knife treatment. However, such treatment should not be preferred after all. It is only suitable for those with particularly poor physical condition, recurrence even after multiple operations, postoperative residual or those who resolutely do not accept the surgery, and must be chosen carefully for the reason of more disadvantages.  3.Drug treatment Those with hypopituitarism can be given drug replacement therapy, and adenomas with secretory function can choose drugs that inhibit excessive secretion of pituitary hormones as appropriate. Some of the adenomas with secretory function can be treated with drugs under the long-term guidance of doctors, such as most of the prolactin adenomas can be treated with long-term oral bromocriptine, and most of them can get good results.  Growth hormone adenomas can be treated with growth inhibitors, and cycloheximide is indicated for ACTH adenomas and GH adenomas. Non-secretory functional adenomas can be treated with alternative therapy such as prednisone and thyroxine tablets to improve the symptoms of hypopituitarism, which are chosen according to the needs of the disease.