In order to survive, they fought with insects and animals, fought with natural disasters, cold and heat, and fought with tribal groups, and often suffered from wounds, tears, bleeding, infections, water and fire burns, insect and animal bites, etc. At the beginning, they used grass, wood, bark and clay to dress wounds, and used stones and bone needles to release blood, drain pus and clean wounds. Internal, external, gynecological, pediatric before the formation. The earliest surviving ancient medical book in China, “52 Disease Formula”, contains the treatment of carbuncles and sores, skin scabies, hemorrhoids and warts, the use of ointment method, the dispersant smoke method, the medicinal bath method, as well as acupuncture, moxibustion, angle method (equivalent to cupping), massage, etc., the use of ligature and excision method to treat hemorrhoids (take the rope, cut with a knife), the original and ancient method to remove anal fistula. China’s first masterpiece of medical theory, the Yellow Emperor’s Classic of Internal Medicine, contains the treatment of gangrene by toe amputation, as well as ironing and moxibustion.