Acute myocardial infarction (AMI) is a sudden complete occlusion or near blockage of a branch of the coronary artery, resulting in prolonged ischemia and necrosis of part of the myocardial cells. The chest pain is the same as angina pectoris, but it is more severe, with a sense of near death, and lasts for more than 30 minutes. Xiao Shiliang, Department of Cardiac Surgery, Wuhan Union Hospital [Treatment] Acute heart attack should be treated in hospital. First, general treatment, absolute bed rest, into the easily digestible diet. Keep the bowels open (available fruit guide). Sedation. Oxygen: general nasal catheter oxygen administration, oxygen flow 2-4L; analgesic drugs, attention must be paid to its side effects such as blood pressure drop, respiratory depression and vomiting; monitoring: electrocardiography, blood pressure and respiration, heart rate, heart rhythm, urine volume monitoring, open veins. II. Restriction and reduction of infarct area (a) drug therapy ① nitroglycerin intravenous drip, use with caution in hypotension, hypovolemia or tachycardia; ② beta-blocker, appropriate for high blood pressure, rapid heart rate, significant ST rise and chest pain. Contraindicated in heart failure, hypotension and slow-onset arrhythmias; ③calcium blockers, there is no evidence that they can reduce the infarct size. If combined with severe hypertension or coronary artery spasm, nifedipine and thiazepine can be used, and the contraindications should be noted. (B) Thrombolytic therapy ① Indications: Q-wave infarction within 6h of acute infarction onset (preferably within 4h). (2) Contraindications: recent active bleeding or bleeding tendency, severe hypertension, cerebrovascular disease, severe liver and kidney disease, advanced age (age > 70 years); (3) Commonly used drugs and usage: streptokinase, urokinase and tissue-type fibrinogen activator, whose main complication is bleeding, especially intracranial bleeding can be life-threatening. They should be noted. (iii) Emergency percutaneous transluminal angioplasty (PTCA) and surgical bypass surgery: for patients with contraindication to thrombolysis or failed thrombolysis, and for patients with severe residual stenosis after thrombolysis, PTCA or surgical bypass surgery should be performed at an elective stage. The treatment of AMI complications (secondary prevention) (a) treatment of coronary heart disease risk factors: hyperlipidemia is appropriate to control the diet, low-fat, low-carbohydrate, high Fruits and vegetables diet, daily fat intake is limited to 30% of total calories, while being treated with lipid-lowering drugs, several commonly used lipid-regulating drugs: (1) polyenecon, (2) Norhombo, (3) lipid-lowering isopropyl ester, (4) niacin, which can reduce triglycerides and low-density cholesterol. Treatment of hypertension and diabetes mellitus and smoking cessation; (2) continued pharmacological treatment with anti-cardiac pain, aspirin, beta-blockers; (3) completion of the following tests: nuclear exercise myocardiography, cardiac blood pool angiography, echocardiography, ambulatory electrocardiography, late potentials. If ischemic myocardium is still present, coronary angiography should be performed, and interventional treatment such as PTCA or coronary artery bypass grafting should be performed if necessary. Chinese herbal medicine can be used to restore Yang and save the rebellion, such as Sihui Tang, Dushan Tang or Ginseng Soup, which are effective for heart attack with low blood pressure or shock. For the manifestation of yin deficiency, Raw Pulse Drink can be used. In western medicine treatment, optional Chinese herbal medicine and acupuncture can be helpful for recovery. The dosage and usage of the above drugs are subject to medical advice.