Many people with Parkinson’s disease have trouble describing what their doctor needs to know at the follow-up appointment. In fact, with a little care, you can usually take notes and bring them to the appointment to clarify the problem and save time. These questions include: 1. about the effect of medication: including how long did it take to work after each dose? Was there any meal that did not work or did not work? How did it behave after the onset of action? Is there an increase in the degree of variability that more than affects activity? The duration of the drug effect? 2, about drug side effects: various discomforts after taking the drug, especially gastrointestinal (nausea, vomiting), abnormal urination and defecation (urinary difficulties, constipation), mental status changes (drowsiness, hallucinations, impulsivity, etc.), cardiac discomfort (panic, etc.), may be common problems caused by Parkinson’s disease drugs.