The clinical manifestations of parathyroid adenoma are mainly due to hypercalcemia, with various clinical manifestations, some patients can show recurrent urinary stones; some patients can show bone pain or even pathological fracture; some patients can show loss of appetite, abdominal distension, constipation, malignancy and other digestive symptoms; some patients can show fatigue, arrhythmia, etc. Diagnosis of parathyroid adenoma 1. Laboratory tests: elevated serum calcium, significantly elevated parathyroid hormone (PTH), 2. Localization tests: technetium-99m nuclear scan: can clarify the location of the tumor. Ultrasound of neck: it can clarify the location of tumor and determine the nature of tumor (benign or malignant) Enhanced CT of neck and chest: if the tumor is large or suspected to be malignant, enhanced CT examination is needed to clarify the scope of tumor and the relationship with surrounding important organs and blood vessels. Treatment of parathyroid adenoma is mainly surgical treatment. The key is to remove the tumor completely and protect the function of the laryngeal recurrent nerve. If the parathyroid hormone level decreases by more than 50% compared with that before surgery, it is a reliable indicator of successful surgery. IV. Precautions after parathyroid adenoma Within 24 hours after surgery, pay attention to observe the wound condition and avoid coughing hard to prevent wound bleeding. Timely recheck serum calcium to prevent the occurrence of hypocalcemia.