Chronic urticaria is difficult to break and can be treated systematically to reduce the number of recurrences. The main treatments are drug therapy and lifestyle improvement. 1. Medication: patients can choose antihistamines for treatment as prescribed by doctors, such as cetirizine, chlorpheniramine maleate, etc., so as to make the patients’ condition under effective control and improve the quality of life. 2. Lifestyle improvement: Avoid exposure to triggering factors, such as pollen, additives in certain foods, etc. Meanwhile, patients need to actively treat the primary disease, such as Helicobacter pylori infection and internal diseases. Avoid over-intense sports, such as sprinting, track and field, basketball, etc. All of the above medications should be used under the guidance of a doctor, avoid self-medication. It is recommended that patients go to the hospital in time and receive standardized treatment under the guidance of the doctor.