Increased sweating after cold is one of the symptoms of spinal cord cavitation. Spinal cord cavitation is a bizarre sweating phenomenon of increased sweating after cold, accompanied by decreased temperature, hyperkeratosis of fingertips and nails, atrophy, and loss of luster. Due to the loss of pain and temperature sensation, burns and bruises and trauma are likely to occur. Late stage patients develop urinary and faecal disorders and recurrent urinary tract infections. The age of onset is 31 to 50 years old, and it is rare in children and the elderly. There are more males than females, and a family history has been reported. The clinical manifestations of spinal cord cavitation are threefold, and the degree of symptoms is strongly related to the early and late development of the cavity. The disease generally progresses slowly, and the early symptoms appear in a segmental distribution, affecting the upper extremities first. When the cavity expands further, the gray matter in the medulla and the white matter conduction bundles outside it are also involved, and conduction bundle dysfunction occurs below the cavity cavity. Therefore, the symptoms of patients in the early stage are limited and mild, while in the late stage, the symptoms are extensive and even paraplegia occurs. Sensory symptoms According to the cavity is located in the cervical and upper thoracic segments of the spinal cord, it is on one side or in the center, and segmental sensory disorders of the upper limbs and upper thoracic segments appear unilaterally, often characterized by segmental dissociative sensory disorders. Pain and temperature sensation are reduced or absent, but deep sensation is present. The symptoms may also be bilateral. 2. Motor symptoms The cervical and thoracic cavities affect the anterior horn of the spinal cord, and symptoms of flaccid partial paralysis of one or both upper limbs appear. The symptoms are muscle weakness and decreased muscle tone, especially the atrophy of interosseous and interosseous muscles of both hands is most obvious, and the severe cases show claw-shaped hand deformity. If the lower trigeminal nerve root is affected, there is a central type of nociceptive and thermo-sensory impairment on the ipsilateral side of the face, and the facial detached sensory loss forms the so-called “onion-like distribution”, accompanied by weakness of masticatory muscles. If the vestibulocerebellar tract is involved, vertigo, nausea, vomiting, gait instability and nystagmus may occur. In one or both lower extremities, supramotor partial paresis occurs, with hypertonia, loss of abdominal wall reflexes and positive Babinski’s sign. In advanced cases, the paralysis is more aggravated. 3. Autonomic damage symptoms The cavity involves the sympathetic spinal center of the lateral horn of the spinal cord (cervical 8 and thoracic 1), and Horner’s syndrome appears. The lesion may damage the skin of the corresponding segment, limb and trunk with abnormal secretion, and hyperhidrosis or hypohidrosis is the only sign of abnormal secretion. Hypohidrosis may be confined to one side of the body, called “hemianopsia”, and is more commonly seen on one side of the upper body, or one upper extremity or half of the face. Often the corneal reflex is also diminished or absent, as neurotrophic keratitis can lead to bilateral corneal perforation. Another bizarre sweating phenomenon is increased sweating when cold, accompanied by a decrease in temperature, hyperkeratosis of the fingertips and nails, atrophy, and loss of luster. Due to the loss of pain and temperature sensation, burns and bruises and trauma are likely to occur. In the late stage, patients develop urinary and faecal disorders and recurrent urinary tract infections.