The application of the antagonistic stimulation method in relieving the muscle spasm is reviewed in this paper. Zhang Jiankui, Department of Pediatrics, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine [Keywords] spasm; antagonistic muscle; spastic muscle; cross-inhibition; review Application of the antagonistic stimulation method in relieving the muscle spasm Abstract: spasm is one of the main factors affecting the central nervous system. of the main factors affecting the central nervous injury patient’s limb movement and prognosis, the traditional physical therapy are mostly focusing on The recent development has shown that stimulating the antagonistic muscle as a means to relieve the spasm has better Which based on the reciprocal inhibition theory,This paper will investigate the new approach on its Key words: spasm; antagonistic muscle;; spastic muscle; reciprocal inhibition; review Spasticity is one of the positive manifestations of upper motor neuron injury and is characterized by a velocity-dependent increase in muscle tone accompanied by hyperactive tendon reflexes. The negative manifestations include muscle weakness, loss of selective motor control, sensory deficits and muscle strength imbalance [1]. The occurrence of spasticity can affect the motor function and balance of the limb and affect the blood circulation of the spastic tissue [2], and prolonged spasticity can result in limb contracture due to muscle shortening. Therefore, myospasm is one of the main factors affecting the movement and prognosis of patients’ limbs. The current treatments for spasticity are mainly physical therapy, pharmacotherapy, surgery and many other methods. Most of these methods, in terms of the site of action, start from the spastic muscle group and play the purpose of directly relieving spasticity. In recent years, some domestic scholars advocate starting from the antagonist muscle group of the patient, in order to improve the excitability of the antagonist muscle of the spastic muscle group and relieve muscle tension as a means, and have achieved good rehabilitation results. The main theoretical basis is the principle of cross-inhibition [3]: if the extension of a muscle (extensor excitation) is induced, the muscle antagonistic to it (flexor muscle) relaxes. The reason for this is that the afferent impulses of the Ia afferent fibers can also connect to the interneurons through the lateral branches of the Ia fibers, forming connections with other synergic and antagonistic motor neurons to excite the synergic muscle and inhibit the antagonistic muscle, showing cross-inhibition. In this paper, the treatment methods to achieve spasticity relief by stimulating antagonist muscles in recent years are summarized as follows. Acupuncture has become one of the important treatments after stroke rehabilitation, and there are two different views on the clinical treatment of hemiplegia [4], one of which advocates acupuncture points on the inferior side of spasticity (non-spastic side, i.e., antagonistic muscles), such as Quchi, Handsanli, Waiguan, Hegu, and Houxi on the upper extremity; and Guizhong, Chengshan, Blood Sea, Yinlingquan, Sanyinjiao, and Zhaohai on the lower extremity. The results of the study showed that acupuncture of the antagonist muscle is an effective method for treating spastic hemiplegia after stroke. 1.1 Acupuncture Jiang [4] observed the effects of acupuncture of the antagonist muscle and the active muscle on the degree of spasticity, clinical spasticity index (CSI), and ability of daily living (ADL) in post-stroke spastic hemiplegia by acupuncture. The results showed that acupuncture of the antagonist muscle group could significantly reduce the spasticity and clinical spasticity index and increase the ADL of the patients, while acupuncture of the active muscle group could only increase the ADL of the patients and did not reduce the spasticity and clinical spasticity index of the patients. This leads to the conclusion that acupuncture of the antagonist muscle is an effective treatment for post-stroke spastic hemiplegia. Zhang [5] observed the efficacy of the antagonist muscle acupuncture method in the treatment of limb spasticity caused by stroke and traumatic brain injury. Ninety patients were randomly divided into two groups and treated with the antagonistic muscle acupuncture method and the conventional acupuncture method, respectively. The total effective rate was 57.78% in the antagonistic muscle acupuncture group and 44.44% in the conventional acupuncture group, with a statistically significant difference between the two groups (P